The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii

BACKGROUND: The interferon-inducible immunity-related GTPases (IRG proteins/p47 GTPases) are a distinctive family of GTPases that function as powerful cell-autonomous resistance factors. The IRG protein, Irga6 (IIGP1), participates in the disruption of the vacuolar membrane surrounding the intracell...

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Detalles Bibliográficos
Autores principales: Pawlowski, Nikolaus, Khaminets, Aliaksandr, Hunn, Julia P, Papic, Natasa, Schmidt, Andreas, Uthaiah, Revathy C, Lange, Rita, Vopper, Gabriela, Martens, Sascha, Wolf, Eva, Howard, Jonathan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042988/
https://www.ncbi.nlm.nih.gov/pubmed/21276251
http://dx.doi.org/10.1186/1741-7007-9-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042988/
https://www.ncbi.nlm.nih.gov/pubmed/21276251
http://dx.doi.org/10.1186/1741-7007-9-7

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