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The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii

BACKGROUND: The interferon-inducible immunity-related GTPases (IRG proteins/p47 GTPases) are a distinctive family of GTPases that function as powerful cell-autonomous resistance factors. The IRG protein, Irga6 (IIGP1), participates in the disruption of the vacuolar membrane surrounding the intracell...

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Detalles Bibliográficos
Autores principales:	Pawlowski, Nikolaus, Khaminets, Aliaksandr, Hunn, Julia P, Papic, Natasa, Schmidt, Andreas, Uthaiah, Revathy C, Lange, Rita, Vopper, Gabriela, Martens, Sascha, Wolf, Eva, Howard, Jonathan C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042988/ https://www.ncbi.nlm.nih.gov/pubmed/21276251 http://dx.doi.org/10.1186/1741-7007-9-7

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