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Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

The mammalian circadian clock uses interlocked negative feedback loops in which the heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master regulator. While there is prominent control of liver functions by the circadian clock, the detailed links between circadian regulators...

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Detalles Bibliográficos
Autores principales: Rey, Guillaume, Cesbron, François, Rougemont, Jacques, Reinke, Hans, Brunner, Michael, Naef, Felix
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043000/
https://www.ncbi.nlm.nih.gov/pubmed/21364973
http://dx.doi.org/10.1371/journal.pbio.1000595