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A Context-Specific Role for Retinoblastoma Protein-Dependent Negative Growth Control in Suppressing Mammary Tumorigenesis

BACKGROUND: The ability to respond to anti-growth signals is critical to maintain tissue homeostasis and loss of this negative growth control safeguard is considered a hallmark of cancer. Negative growth regulation generally occurs during the G0/G1 phase of the cell cycle, yet the redundancy and com...

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Detalles Bibliográficos
Autores principales: Francis, Sarah M., Chakrabarti, Subrata, Dick, Frederick A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043004/
https://www.ncbi.nlm.nih.gov/pubmed/21364977
http://dx.doi.org/10.1371/journal.pone.0016434