An Effective Assessment of Simvastatin-Induced Toxicity with NMR-Based Metabonomics Approach

BACKGROUND: Simvastatin, which is used to control elevated cholesterol levels, is one of the most widely prescribed drugs. However, a daily excessive dose can induce drug-toxicity, especially in muscle and liver. Current markers for toxicity reflect mostly the late stages of tissue damage; thus, mor...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hye-ji, Choi, Myung-Joo, Wen, He, Kwon, Hyuk Nam, Jung, Kyung Hee, Hong, Sang-Won, Kim, Joon Mee, Hong, Soon-Sun, Park, Sunghyouk
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043067/
https://www.ncbi.nlm.nih.gov/pubmed/21364936
http://dx.doi.org/10.1371/journal.pone.0016641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043067/
https://www.ncbi.nlm.nih.gov/pubmed/21364936
http://dx.doi.org/10.1371/journal.pone.0016641

Ejemplares similares