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Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

BACKGROUND: No animal models of autism spectrum disorders (ASD) with good construct validity are currently available; using genetic models of pathologies characterized by ASD-like deficits, but with known causes, may be therefore a promising strategy. The Fmr1-KO mouse is an example of this approach...

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Detalles Bibliográficos
Autores principales: Pietropaolo, Susanna, Guilleminot, Aurélie, Martin, Benoît, D'Amato, Francesca R., Crusio, Wim E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043074/
https://www.ncbi.nlm.nih.gov/pubmed/21364941
http://dx.doi.org/10.1371/journal.pone.0017073