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Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice
INTRODUCTION: Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence. Shortening of telomeres has been shown to occur during human aging and in chronic diseases that accelerate cell tu...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043103/ https://www.ncbi.nlm.nih.gov/pubmed/21364961 http://dx.doi.org/10.1371/journal.pone.0017122 |