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Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice

INTRODUCTION: Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence. Shortening of telomeres has been shown to occur during human aging and in chronic diseases that accelerate cell tu...

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Detalles Bibliográficos
Autores principales: von Figura, Guido, Wagner, Martin, Nalapareddy, Kodandaramireddy, Hartmann, Daniel, Kleger, Alexander, Guachalla, Luis Miguel, Rolyan, Harshvardhan, Adler, Guido, Rudolph, Karl Lenhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043103/
https://www.ncbi.nlm.nih.gov/pubmed/21364961
http://dx.doi.org/10.1371/journal.pone.0017122