VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease

Dopamine is transported into synaptic vesicles by the vesicular monoamine transporter (VMAT2; SLC18A2). Disruption of dopamine storage has been hypothesized to damage the dopamine neurons that are lost in Parkinson's disease. By disrupting vesicular storage of dopamine and other monoamines, we...

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Detalles Bibliográficos
Autores principales: Taylor, Tonya N., Caudle, W. Michael, Miller, Gary W.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043293/
https://www.ncbi.nlm.nih.gov/pubmed/21403896
http://dx.doi.org/10.4061/2011/124165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043293/
https://www.ncbi.nlm.nih.gov/pubmed/21403896
http://dx.doi.org/10.4061/2011/124165

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