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Development of Novel In Silico Model to Predict Corneal Permeability for Congeneric Drugs: A QSPR Approach

This study was undertaken to determine in vivo permeability coefficients for fluoroquinolones and to assess its correlation with the permeability derived using reported models in the literature. Further, the aim was to develop novel QSPR model to predict corneal permeability for fluoroquinolones and...

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Detalles Bibliográficos
Autores principales: Sharma, Charu, Velpandian, Thirumurthy, Biswas, Nihar Ranjan, Nayak, Niranjan, Vajpayee, Rasik Bihari, Ghose, Supriyo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043298/
https://www.ncbi.nlm.nih.gov/pubmed/21403901
http://dx.doi.org/10.1155/2011/483869