Evaluation of RNA-knockdown strategies for modulation of cytochrome P450 reductase activity in mouse hepatocytes

Transgenic technologies can provide important animal models for studying drug-metabolizing enzymes. Our overall aim was to generate versatile cell and animal systems that exhibited varying levels of cytochrome P450 oxidoreductase (POR) activity, more accurately modelling the human population for pha...

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Detalles Bibliográficos
Autores principales: Mackenzie, Neil CW, Lillico, Simon G, Brown, Ken, Wolf, Charles R, Whitelaw, Christopher BA
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2010
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043560/
https://www.ncbi.nlm.nih.gov/pubmed/21350684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043560/
https://www.ncbi.nlm.nih.gov/pubmed/21350684

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