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TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells
Reactive oxygen species (ROS) are generated as a result of normal cellular metabolism, mainly through the mitochondria and peroxisomes, but their release is enhanced by the activation of oxidant enzymes such as NADPH oxidases or downregulation of endogenous antioxidant enzymes such as manganese-supe...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043811/ https://www.ncbi.nlm.nih.gov/pubmed/21131394 http://dx.doi.org/10.1152/ajplung.00134.2010 |