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TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells

Reactive oxygen species (ROS) are generated as a result of normal cellular metabolism, mainly through the mitochondria and peroxisomes, but their release is enhanced by the activation of oxidant enzymes such as NADPH oxidases or downregulation of endogenous antioxidant enzymes such as manganese-supe...

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Detalles Bibliográficos
Autores principales: Michaeloudes, Charalambos, Sukkar, Maria B., Khorasani, Nadia M., Bhavsar, Pankaj K., Chung, Kian Fan
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043811/
https://www.ncbi.nlm.nih.gov/pubmed/21131394
http://dx.doi.org/10.1152/ajplung.00134.2010