Atomic Force Microscopy-Based Screening of Drug-Excipient Miscibility and Stability of Solid Dispersions

PURPOSE: Development of a method to assess the drug/polymer miscibility and stability of solid dispersions using a melt-based mixing method. METHODS: Amorphous fractured films are prepared and characterized with Raman Microscopy in combination with Atomic Force Microscopy to discriminate between hom...

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Detalles Bibliográficos
Autores principales: Lauer, Matthias Eckhard, Grassmann, Olaf, Siam, Monira, Tardio, Joseph, Jacob, Laurence, Page, Susanne, Kindt, Johannes Heinrich, Engel, Andreas, Alsenz, Jochem
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044090/
https://www.ncbi.nlm.nih.gov/pubmed/21046435
http://dx.doi.org/10.1007/s11095-010-0306-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044090/
https://www.ncbi.nlm.nih.gov/pubmed/21046435
http://dx.doi.org/10.1007/s11095-010-0306-4

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