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The influence of bisphosphonates on human osteoblast migration and integrin aVb3/tenascin C gene expression in vitro

BACKGROUND: Bisphosphonates are therapeutics of bone diseases, such as Paget's disease, multiple myeloma or osteoclastic metastases. As a severe side effect the bisphosphonate induced osteonecrosis of the jaw (BONJ) often requires surgical treatment and is accompanied with a disturbed wound hea...

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Detalles Bibliográficos
Autores principales: Koch, Felix P, Wunsch, Annette, Merkel, Christina, Ziebart, Thomas, Pabst, Andreas, Said Yekta, Sareh, Blessmann, Marco, Smeets, Ralf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044099/
https://www.ncbi.nlm.nih.gov/pubmed/21299894
http://dx.doi.org/10.1186/1746-160X-7-4