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Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling

BACKGROUND: The wounding response relies on tightly regulated crosstalk between recruited fibroblasts and the collagenous extracellular matrix (ECM). Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor for fibrillar collagen expressed during pathologic scarring, for example wound healin...

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Detalles Bibliográficos
Autores principales: Olaso, Elvira, Lin, Hsin-Chieh, Wang, Li-Hsien, Friedman, Scott L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044108/
https://www.ncbi.nlm.nih.gov/pubmed/21288331
http://dx.doi.org/10.1186/1755-1536-4-5