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Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling
BACKGROUND: The wounding response relies on tightly regulated crosstalk between recruited fibroblasts and the collagenous extracellular matrix (ECM). Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor for fibrillar collagen expressed during pathologic scarring, for example wound healin...
Autores principales: | Olaso, Elvira, Lin, Hsin-Chieh, Wang, Li-Hsien, Friedman, Scott L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044108/ https://www.ncbi.nlm.nih.gov/pubmed/21288331 http://dx.doi.org/10.1186/1755-1536-4-5 |
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