Tem1 localization to the spindle pole bodies is essential for mitotic exit and impairs spindle checkpoint function

The mitotic exit network (MEN) is a signaling cascade that triggers inactivation of the mitotic cyclin-dependent kinases and exit from mitosis. The GTPase Tem1 localizes on the spindle pole bodies (SPBs) and initiates MEN signaling. Tem1 activity is inhibited until anaphase by Bfa1-Bub2. These prote...

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Detalles Bibliográficos
Autores principales: Valerio-Santiago, Mauricio, Monje-Casas, Fernando
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044116/
https://www.ncbi.nlm.nih.gov/pubmed/21321099
http://dx.doi.org/10.1083/jcb.201007044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044116/
https://www.ncbi.nlm.nih.gov/pubmed/21321099
http://dx.doi.org/10.1083/jcb.201007044

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