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Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells

Natural killer (NK) lymphocytes use a variety of activating receptors to recognize and kill infected or tumorigenic cells during an innate immune response. To prevent targeting healthy tissue, NK cells also express numerous inhibitory receptors that signal through immunotyrosine-based inhibitory mot...

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Detalles Bibliográficos
Autores principales: Abeyweera, Thushara P., Merino, Ernesto, Huse, Morgan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044118/
https://www.ncbi.nlm.nih.gov/pubmed/21339333
http://dx.doi.org/10.1083/jcb.201009135