The HLA Class II Allele DRB1*1501 Is Over-Represented in Patients with Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and medically refractory lung disease with a grim prognosis. Although the etiology of IPF remains perplexing, abnormal adaptive immune responses are evident in many afflicted patients. We hypothesized that perturbations of human leukoc...

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Detalles Bibliográficos
Autores principales: Xue, Jianmin, Gochuico, Bernadette R., Alawad, Ahmad Samer, Feghali-Bostwick, Carol A., Noth, Imre, Nathan, Steven D., Rosen, Glenn D., Rosas, Ivan O., Dacic, Sanja, Ocak, Iclal, Fuhrman, Carl R., Cuenco, Karen T., Smith, Mary A., Jacobs, Susan S., Zeevi, Adriana, Morel, Penelope A., Pilewski, Joseph M., Valentine, Vincent G., Gibson, Kevin F., Kaminski, Naftali, Sciurba, Frank C., Zhang, Yingze, Duncan, Steven R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044131/
https://www.ncbi.nlm.nih.gov/pubmed/21373184
http://dx.doi.org/10.1371/journal.pone.0014715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044131/
https://www.ncbi.nlm.nih.gov/pubmed/21373184
http://dx.doi.org/10.1371/journal.pone.0014715

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