Adenylate Cyclase Toxin Promotes Internalisation of Integrins and Raft Components and Decreases Macrophage Adhesion Capacity

Bordetella pertussis, the bacterium that causes whooping cough, secretes an adenylate cyclase toxin (ACT) that must be post-translationally palmitoylated in the bacterium cytosol to be active. The toxin targets phagocytes expressing the CD11b/CD18 integrin receptor. It delivers a catalytic adenylate...

Descripción completa

Detalles Bibliográficos
Autores principales: Martín, César, Uribe, Kepa B., Gómez-Bilbao, Geraxane, Ostolaza, Helena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044178/
https://www.ncbi.nlm.nih.gov/pubmed/21383852
http://dx.doi.org/10.1371/journal.pone.0017383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044178/
https://www.ncbi.nlm.nih.gov/pubmed/21383852
http://dx.doi.org/10.1371/journal.pone.0017383

Ejemplares similares