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Effect of Immune Pressure on Hepatitis C Virus Evolution: Insights From a Single-Source Outbreak

The host's immune response to hepatitis C virus (HCV) can result in the selection of characteristic mutations (adaptations) that enable the virus to escape this response. The ability of the virus to mutate at these sites is dependent on the incoming virus, the fitness cost incurred by the mutat...

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Detalles Bibliográficos
Autores principales: Merani, Shahzma, Petrovic, Danijela, James, Ian, Chopra, Abha, Cooper, Don, Freitas, Elizabeth, Rauch, Andri, di Iulio, Julia, John, Mina, Lucas, Michaela, Fitzmaurice, Karen, McKiernan, Susan, Norris, Suzanne, Kelleher, Dermot, Klenerman, Paul, Gaudieri, Silvana
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044208/
https://www.ncbi.nlm.nih.gov/pubmed/21246583
http://dx.doi.org/10.1002/hep.24076