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Effect of Immune Pressure on Hepatitis C Virus Evolution: Insights From a Single-Source Outbreak
The host's immune response to hepatitis C virus (HCV) can result in the selection of characteristic mutations (adaptations) that enable the virus to escape this response. The ability of the virus to mutate at these sites is dependent on the incoming virus, the fitness cost incurred by the mutat...
Autores principales: | Merani, Shahzma, Petrovic, Danijela, James, Ian, Chopra, Abha, Cooper, Don, Freitas, Elizabeth, Rauch, Andri, di Iulio, Julia, John, Mina, Lucas, Michaela, Fitzmaurice, Karen, McKiernan, Susan, Norris, Suzanne, Kelleher, Dermot, Klenerman, Paul, Gaudieri, Silvana |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044208/ https://www.ncbi.nlm.nih.gov/pubmed/21246583 http://dx.doi.org/10.1002/hep.24076 |
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