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An efficient algorithmic approach for mass spectrometry-based disulfide connectivity determination using multi-ion analysis

BACKGROUND: Determining the disulfide (S-S) bond pattern in a protein is often crucial for understanding its structure and function. In recent research, mass spectrometry (MS) based analysis has been applied to this problem following protein digestion under both partial reduction and non-reduction c...

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Detalles Bibliográficos
Autores principales: Murad, William, Singh, Rahul, Yen, Ten-Yang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044266/
https://www.ncbi.nlm.nih.gov/pubmed/21342541
http://dx.doi.org/10.1186/1471-2105-12-S1-S12