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Strobe sequence design for haplotype assembly

BACKGROUND: Humans are diploid, carrying two copies of each chromosome, one from each parent. Separating the paternal and maternal chromosomes is an important component of genetic analyses such as determining genetic association, inferring evolutionary scenarios, computing recombination rates, and d...

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Detalles Bibliográficos
Autores principales: Lo, Christine, Bashir, Ali, Bansal, Vikas, Bafna, Vineet
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044279/
https://www.ncbi.nlm.nih.gov/pubmed/21342554
http://dx.doi.org/10.1186/1471-2105-12-S1-S24