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Predicting gene expression in T cell differentiation from histone modifications and transcription factor binding affinities by linear mixture models
BACKGROUND: The differentiation process from stem cells to fully differentiated cell types is controlled by the interplay of chromatin modifications and transcription factor activity. Histone modifications or transcription factors frequently act in a multi-functional manner, with a given DNA motif o...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044284/ https://www.ncbi.nlm.nih.gov/pubmed/21342559 http://dx.doi.org/10.1186/1471-2105-12-S1-S29 |