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Fast and accurate clustering of noncoding RNAs using ensembles of sequence alignments and secondary structures

BACKGROUND: Clustering of unannotated transcripts is an important task to identify novel families of noncoding RNAs (ncRNAs). Several hierarchical clustering methods have been developed using similarity measures based on the scores of structural alignment. However, the high computational cost of exa...

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Detalles Bibliográficos
Autores principales: Saito, Yutaka, Sato, Kengo, Sakakibara, Yasubumi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044305/
https://www.ncbi.nlm.nih.gov/pubmed/21342580
http://dx.doi.org/10.1186/1471-2105-12-S1-S48