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A regression analysis of gene expression in ES cells reveals two gene classes that are significantly different in epigenetic patterns

BACKGROUND: To understand the gene regulatory system that governs the self-renewal and pluripotency of embryonic stem cells (ESCs) is an important step for promoting regenerative medicine. In it, the role of several core transcription factors (TFs), such as Oct4, Sox2 and Nanog, has been intensively...

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Detalles Bibliográficos
Autores principales: Park, Sung-Joon, Nakai, Kenta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044308/
https://www.ncbi.nlm.nih.gov/pubmed/21342583
http://dx.doi.org/10.1186/1471-2105-12-S1-S50