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A regression analysis of gene expression in ES cells reveals two gene classes that are significantly different in epigenetic patterns
BACKGROUND: To understand the gene regulatory system that governs the self-renewal and pluripotency of embryonic stem cells (ESCs) is an important step for promoting regenerative medicine. In it, the role of several core transcription factors (TFs), such as Oct4, Sox2 and Nanog, has been intensively...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044308/ https://www.ncbi.nlm.nih.gov/pubmed/21342583 http://dx.doi.org/10.1186/1471-2105-12-S1-S50 |