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Linkage disequilibrium based genotype calling from low-coverage shotgun sequencing reads

BACKGROUND: Recent technology advances have enabled sequencing of individual genomes, promising to revolutionize biomedical research. However, deep sequencing remains more expensive than microarrays for performing whole-genome SNP genotyping. RESULTS: In this paper we introduce a new multi-locus sta...

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Detalles Bibliográficos
Autores principales: Duitama, Jorge, Kennedy, Justin, Dinakar, Sanjiv, Hernández, Yözen, Wu, Yufeng, Măndoiu, Ion I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044311/
https://www.ncbi.nlm.nih.gov/pubmed/21342586
http://dx.doi.org/10.1186/1471-2105-12-S1-S53