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Molecular Model of Prion Transmission to Humans

To assess interspecies barriers to transmission of transmissible spongiform encephalopathies, we investigated the ability of disease-associated prion proteins (PrP(d)) to initiate conversion of the human normal cellular form of prion protein of the 3 major PRNP polymorphic variants in vitro. Protein...

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Detalles Bibliográficos
Autores principales: Jones, Michael, Wight, Darren, Barron, Rona, Jeffrey, Martin, Manson, Jean, Prowse, Christopher, Ironside, James W., Head, Mark W.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044515/
https://www.ncbi.nlm.nih.gov/pubmed/19961689
http://dx.doi.org/10.3201/eid1512.090194