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Synergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinoma

BACKGROUND: Adeno-associated virus-2 (AAV-2)-mediated gene therapy is quite suitable for local or regional application in head and neck cancer squamous cell carcinoma (HNSCC). However, its low transduction efficiency has limited its further development as a therapeutic agent. DNA damaging agents hav...

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Detalles Bibliográficos
Autores principales: Jiang, Minghong, Liu, Zheng, Xiang, Yang, Ma, Hong, Liu, Shilian, Liu, Yanxin, Zheng, Dexian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044652/
https://www.ncbi.nlm.nih.gov/pubmed/21291526
http://dx.doi.org/10.1186/1471-2407-11-54