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Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle

BACKGROUND: Divergently selected Lean and Fat mouse lines represent unique models for a polygenic form of resistance and susceptibility to obesity development. Previous research on these lines focused mainly on obesity-susceptible factors in the Fat line. This study aimed to examine the molecular ba...

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Detalles Bibliográficos
Autores principales: Simončič, Matjaž, Režen, Tadeja, Juvan, Peter, Rozman, Damjana, Fazarinc, Gregor, Fievet, Catherine, Staels, Bart, Horvat, Simon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044672/
https://www.ncbi.nlm.nih.gov/pubmed/21291556
http://dx.doi.org/10.1186/1471-2164-12-96