Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals

Family studies of individual tissues have shown that gene expression traits are genetically heritable. Here, we investigate cis and trans components of heritability both within and across tissues by applying variance-components methods to 722 Icelanders from family cohorts, using identity-by-descent...

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Detalles Bibliográficos
Autores principales: Price, Alkes L., Helgason, Agnar, Thorleifsson, Gudmar, McCarroll, Steven A., Kong, Augustine, Stefansson, Kari
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044684/
https://www.ncbi.nlm.nih.gov/pubmed/21383966
http://dx.doi.org/10.1371/journal.pgen.1001317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044684/
https://www.ncbi.nlm.nih.gov/pubmed/21383966
http://dx.doi.org/10.1371/journal.pgen.1001317

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