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Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Epidemiology and candidate gene studies indicate a shared genetic basis for celiac disease (CD) and rheumatoid arthritis (RA), but the extent of this sharing has not been systematically explored. Previous studies demonstrate that 6 of the established non-HLA CD and RA risk loci (out of 26 loci for e...

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Detalles Bibliográficos
Autores principales: Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Raychaudhuri, Soumya, Festen, Eleanora A., Franke, Lude, Westra, Harm-Jan, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, Gupta, Namrata, Romanos, Jihane, McManus, Ross, Ryan, Anthony W., Turner, Graham, Brouwer, Elisabeth, Posthumus, Marcel D., Remmers, Elaine F., Tucci, Francesca, Toes, Rene, Grandone, Elvira, Mazzilli, Maria Cristina, Rybak, Anna, Cukrowska, Bozena, Coenen, Marieke J. H., Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Li, Yonghong, de Bakker, Paul I. W., Gregersen, Peter K., Worthington, Jane, Siminovitch, Katherine A., Klareskog, Lars, Huizinga, Tom W. J., Wijmenga, Cisca, Plenge, Robert M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044685/
https://www.ncbi.nlm.nih.gov/pubmed/21383967
http://dx.doi.org/10.1371/journal.pgen.1002004