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Episomal Viral cDNAs Identify a Reservoir That Fuels Viral Rebound after Treatment Interruption and That Contributes to Treatment Failure

Viral reservoirs that persist in HIV-1 infected individuals on antiretroviral therapy (ART) are the major obstacle to viral eradication. The identification and definition of viral reservoirs in patients on ART is needed in order to understand viral persistence and achieve the goal of viral eradicati...

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Detalles Bibliográficos
Autores principales: Sharkey, Mark, Babic, Dunja Z., Greenough, Thomas, Gulick, Roy, Kuritzkes, Daniel R., Stevenson, Mario
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044693/
https://www.ncbi.nlm.nih.gov/pubmed/21383975
http://dx.doi.org/10.1371/journal.ppat.1001303