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Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles

If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over HIV replication remains essential. Increased cytotoxic capacity of HIV-specific CD8(+) T-cells associated with efficient elimination of HIV-inf...

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Detalles Bibliográficos
Autores principales: Migueles, Stephen A., Rood, Julia E., Berkley, Amy M., Guo, Tiffany, Mendoza, Daniel, Patamawenu, Andy, Hallahan, Claire W., Cogliano, Nancy A., Frahm, Nicole, Duerr, Ann, McElrath, M. Juliana, Connors, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044701/
https://www.ncbi.nlm.nih.gov/pubmed/21383976
http://dx.doi.org/10.1371/journal.ppat.1002002