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Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles
If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over HIV replication remains essential. Increased cytotoxic capacity of HIV-specific CD8(+) T-cells associated with efficient elimination of HIV-inf...
Autores principales: | Migueles, Stephen A., Rood, Julia E., Berkley, Amy M., Guo, Tiffany, Mendoza, Daniel, Patamawenu, Andy, Hallahan, Claire W., Cogliano, Nancy A., Frahm, Nicole, Duerr, Ann, McElrath, M. Juliana, Connors, Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044701/ https://www.ncbi.nlm.nih.gov/pubmed/21383976 http://dx.doi.org/10.1371/journal.ppat.1002002 |
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