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Type I Interferon Signaling Regulates Ly6C(hi) Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

Type I interferon (IFN-I) plays a critical role in the homeostasis of hematopoietic stem cells and influences neutrophil influx to the site of inflammation. IFN-I receptor knockout (Ifnar1 (−/−)) mice develop significant defects in the infiltration of Ly6C(hi) monocytes in the lung after influenza i...

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Detalles Bibliográficos
Autores principales: Seo, Sang-Uk, Kwon, Hyung-Joon, Ko, Hyun-Jeong, Byun, Young-Ho, Seong, Baik Lin, Uematsu, Satoshi, Akira, Shizuo, Kweon, Mi-Na
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044702/
https://www.ncbi.nlm.nih.gov/pubmed/21383977
http://dx.doi.org/10.1371/journal.ppat.1001304