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Type I Interferon Signaling Regulates Ly6C(hi) Monocytes and Neutrophils during Acute Viral Pneumonia in Mice
Type I interferon (IFN-I) plays a critical role in the homeostasis of hematopoietic stem cells and influences neutrophil influx to the site of inflammation. IFN-I receptor knockout (Ifnar1 (−/−)) mice develop significant defects in the infiltration of Ly6C(hi) monocytes in the lung after influenza i...
Autores principales: | Seo, Sang-Uk, Kwon, Hyung-Joon, Ko, Hyun-Jeong, Byun, Young-Ho, Seong, Baik Lin, Uematsu, Satoshi, Akira, Shizuo, Kweon, Mi-Na |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044702/ https://www.ncbi.nlm.nih.gov/pubmed/21383977 http://dx.doi.org/10.1371/journal.ppat.1001304 |
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