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A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector

The production of cells capable of expressing gene(s) of interest is important for a variety of applications in biomedicine and biotechnology, including gene therapy and animal transgenesis. The ability to insert transgenes at a precise location in the genome, using site-specific recombinases such a...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Shigeyuki, Kazuki, Yasuhiro, Nakayama, Yuji, Nanba, Eiji, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044732/
https://www.ncbi.nlm.nih.gov/pubmed/21390305
http://dx.doi.org/10.1371/journal.pone.0017267