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A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector
The production of cells capable of expressing gene(s) of interest is important for a variety of applications in biomedicine and biotechnology, including gene therapy and animal transgenesis. The ability to insert transgenes at a precise location in the genome, using site-specific recombinases such a...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044732/ https://www.ncbi.nlm.nih.gov/pubmed/21390305 http://dx.doi.org/10.1371/journal.pone.0017267 |