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Specific Oncogenic Activity of the Src-Family Tyrosine Kinase c-Yes in Colon Carcinoma Cells

c-Yes, a member of the Src tyrosine kinase family, is found highly activated in colon carcinoma but its importance relative to c-Src has remained unclear. Here we show that, in HT29 colon carcinoma cells, silencing of c-Yes, but not of c-Src, selectively leads to an increase of cell clustering assoc...

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Detalles Bibliográficos
Autores principales: Sancier, Florence, Dumont, Aurélie, Sirvent, Audrey, Paquay de Plater, Ludmilla, Edmonds, Thomas, David, Géraldine, Jan, Michel, de Montrion, Catherine, Cogé, Francis, Léonce, Stéphane, Burbridge, Michael, Bruno, Alain, Boutin, Jean A., Lockhart, Brian, Roche, Serge, Cruzalegui, Francisco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044743/
https://www.ncbi.nlm.nih.gov/pubmed/21390316
http://dx.doi.org/10.1371/journal.pone.0017237