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The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor

Tumors create a heterogeneous acidic microenvironment which assists their growth and which must be taken into account in the design of drugs and their delivery. In addition, the acidic extracellular pH (pHe) is itself exploited in several experimental techniques for drug delivery. The way the acidit...

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Detalles Bibliográficos
Autores principales: Grillon, Emmanuelle, Farion, Régine, Fablet, Katell, De Waard, Michel, Tse, Chung Ming, Donowitz, Mark, Rémy, Chantal, Coles, Jonathan A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044751/
https://www.ncbi.nlm.nih.gov/pubmed/21390324
http://dx.doi.org/10.1371/journal.pone.0017416