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The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals
BACKGROUND: Rho GTPases control many cellular processes, including cell survival, gene expression and migration. Rho proteins reside mainly in the cytosol and are targeted to the plasma membrane (PM) upon specific activation by guanine nucleotide exchange factors (GEFs). Accordingly, most GEFs are a...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044755/ https://www.ncbi.nlm.nih.gov/pubmed/21390328 http://dx.doi.org/10.1371/journal.pone.0017380 |