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Quantitative Prediction of miRNA-mRNA Interaction Based on Equilibrium Concentrations

MicroRNAs (miRNAs) suppress gene expression by forming a duplex with a target messenger RNA (mRNA), blocking translation or initiating cleavage. Computational approaches have proven valuable for predicting which mRNAs can be targeted by a given miRNA, but currently available prediction methods do no...

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Detalles Bibliográficos
Autores principales: Ragan, Chikako, Zuker, Michael, Ragan, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044769/
https://www.ncbi.nlm.nih.gov/pubmed/21390282
http://dx.doi.org/10.1371/journal.pcbi.1001090