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Quantitative Prediction of miRNA-mRNA Interaction Based on Equilibrium Concentrations
MicroRNAs (miRNAs) suppress gene expression by forming a duplex with a target messenger RNA (mRNA), blocking translation or initiating cleavage. Computational approaches have proven valuable for predicting which mRNAs can be targeted by a given miRNA, but currently available prediction methods do no...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044769/ https://www.ncbi.nlm.nih.gov/pubmed/21390282 http://dx.doi.org/10.1371/journal.pcbi.1001090 |