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Functional Genomics of Serotonin Receptor 2A (HTR2A): Interaction of Polymorphism, Methylation, Expression and Disease Association

Serotonergic neurotransmission plays a key role in the pathophysiology of neuropsychiatric illnesses. The functional significance of a promoter polymorphism, −1438G/A (rs6311), in one of the major genes of this system (serotonin receptor 2A, HTR2A) remains poorly understood in the context of epigene...

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Detalles Bibliográficos
Autores principales: Falkenberg, Virginia R., Gurbaxani, Brian M., Unger, Elizabeth R., Rajeevan, Mangalathu S.
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044825/
https://www.ncbi.nlm.nih.gov/pubmed/20941551
http://dx.doi.org/10.1007/s12017-010-8138-2