Mouse Ataxin-3 Functional Knock-Out Model

Spinocerebellar ataxia 3 (SCA3) is a genetic disorder resulting from the expansion of the CAG repeats in the ATXN3 gene. The pathogenesis of SCA3 is based on the toxic function of the mutant ataxin-3 protein, but the exact mechanism of the disease remains elusive. Various types of transgenic mouse m...

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Detalles Bibliográficos
Autores principales: Switonski, Pawel M., Fiszer, Agnieszka, Kazmierska, Katarzyna, Kurpisz, Maciej, Krzyzosiak, Wlodzimierz J., Figiel, Maciej
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044828/
https://www.ncbi.nlm.nih.gov/pubmed/20945165
http://dx.doi.org/10.1007/s12017-010-8137-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044828/
https://www.ncbi.nlm.nih.gov/pubmed/20945165
http://dx.doi.org/10.1007/s12017-010-8137-3

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