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Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

The Hippo pathway restricts the activity of transcriptional co-activators TAZ and YAP by phosphorylating them for cytoplasmic sequestration or degradation. In this report, we describe an independent mechanism for the cell to restrict the activity of TAZ and YAP through interaction with angiomotin (A...

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Detalles Bibliográficos
Autores principales: Chan, Siew Wee, Lim, Chun Jye, Chong, Yaan Fun, Pobbati, Ajaybabu V., Huang, Caixia, Hong, Wanjin
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044958/
https://www.ncbi.nlm.nih.gov/pubmed/21224387
http://dx.doi.org/10.1074/jbc.C110.212621