Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor

Factor-inhibiting hypoxia-inducible factor (FIH) catalyzes the β-hydroxylation of an asparagine residue in the C-terminal transcriptional activation domain of the hypoxia inducible factor (HIF), a modification that negatively regulates HIF transcriptional activity. FIH also catalyzes the hydroxylati...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Ge, Wei, Chowdhury, Rasheduzzaman, Claridge, Timothy D. W., Kramer, Holger B., Schmierer, Bernhard, McDonough, Michael A., Gong, Lingzhi, Kessler, Benedikt M., Ratcliffe, Peter J., Coleman, Mathew L., Schofield, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045019/
https://www.ncbi.nlm.nih.gov/pubmed/21177872
http://dx.doi.org/10.1074/jbc.M110.193540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045019/
https://www.ncbi.nlm.nih.gov/pubmed/21177872
http://dx.doi.org/10.1074/jbc.M110.193540

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