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Removing Noise From Pyrosequenced Amplicons
BACKGROUND: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequencing technology, 454 pyrosequencing, has allowed much larger read numbers from PCR amplicons than ever before. This has rev...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045300/ https://www.ncbi.nlm.nih.gov/pubmed/21276213 http://dx.doi.org/10.1186/1471-2105-12-38 |