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Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma

BACKGROUND: The genetics of advanced biliary tract cancers (BTC), which encompass intra- and extra-hepatic cholangiocarcinomas as well as gallbladder carcinomas, are heterogeneous and remain to be fully defined. METHODS: To better characterize mutations in established known oncogenes and tumor suppr...

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Detalles Bibliográficos
Autores principales: Deshpande, Vikram, Nduaguba, Afamefuna, Zimmerman, Stephanie M, Kehoe, Sarah M, MacConaill, Laura E, Lauwers, Gregory Y, Ferrone, Cristina, Bardeesy, Nabeel, Zhu, Andrew X, Hezel, Aram F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045359/
https://www.ncbi.nlm.nih.gov/pubmed/21303542
http://dx.doi.org/10.1186/1471-2407-11-60