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Human Pluripotent Stem Cells Differentiated in Fully Defined Medium Generate Hematopoietic CD34(+) and CD34(−) Progenitors with Distinct Characteristics
BACKGROUND: Differentiation of pluripotent stem cells in vitro provides a powerful means to investigate early developmental fates, including hematopoiesis. In particular, the use of a fully defined medium (FDM) would avoid biases induced by unidentified factors contained in serum, and would also all...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045374/ https://www.ncbi.nlm.nih.gov/pubmed/21364915 http://dx.doi.org/10.1371/journal.pone.0014733 |